Young leaves are smoked in pipes for analgesic effects.
Early settlers used the plant to alleviate pain, and Shona healers administer medicines from the plant to cure madness.
In Tanganyika, the fruit of the plant M. flabellifolia - a well known medicinal plant used in various regions of Northern Africa - is smoked with tobac.co or as a tobac.co substitute.
The Zulus call it `uvukwabafile' and also snuff the leaves.
The leaves are snuffed by the Ndebele to chase away evil spirits.
Plants are used to bring good luck in Zimbabwe.
Also used as a tonic; an infusion of the plant is drunk by the Zulu's as a restorative.
http://www.thebotanicalsource.com/id268.htm describes a Myrothamnus that is smoked for psychoactive effects in Madagascar (off the coast of Southern Africa).